TargetMol

JAK2-IN-6

Product Code:
 
TAR-T40443
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T40443-1mg1mg£102.00
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TAR-T40443-5mg5mg£142.00
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TAR-T40443-10mg10mg£173.00
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TAR-T40443-25mg25mg£246.00
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TAR-T40443-50mg50mg£332.00
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TAR-T40443-100mg100mg£461.00
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Quantity:
TAR-T40443-500mg500mg£922.00
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Further Information

Bioactivity:
JAK2-IN-6, a multiple-substituted aminothiazole derivative, is a potent and selective JAK2 inhibitor with an IC 50 of 22.86 μg/mL. JAK2-IN-6 shows no activity against JAK1 and JAK3. JAK2-IN-6 has anti-proliferative effect against cancer cells.
CAS:
353512-04-6
Formula:
C14H10ClN3OS2
Molecular Weight:
335.82
Pathway:
Angiogenesis|JAK/STAT signaling|Stem Cells|Chromatin/Epigenetic
Purity:
0.98
SMILES:
Nc1nc(Nc2ccccc2)sc1C(=O)c1ccc(Cl)s1
Target:
JAK

References

Yao T T, et al. Integration of pharmacophore mapping and molecular docking in sequential virtual screening: towards the discovery of novel JAK2 inhibitors. RSC advances, 2017, 7(17): 10353-10360.