TargetMol

ETC-159

Product Code:
 
TAR-T4043
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4043-5mg5mg£105.00
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Quantity:
TAR-T4043-1mL1 mL * 10 mM (in DMSO)£109.00
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Quantity:
TAR-T4043-10mg10mg£125.00
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Quantity:
TAR-T4043-25mg25mg£172.00
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Quantity:
TAR-T4043-50mg50mg£237.00
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Quantity:
TAR-T4043-100mg100mg£367.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
ETC-159 is a potent, orally available PORCN inhibitor. It inhibits β-catenin reporter activity with an IC50 of 2.9 nM.
CAS:
1638250-96-0
Formula:
C19H17N7O3
Molecular Weight:
391.391
Pathway:
Cytoskeletal Signaling; Stem Cells
Purity:
0.994
SMILES:
Cn1c2ncn(CC(=O)Nc3ccc(nn3)-c3ccccc3)c2c(=O)n(C)c1=O
Target:
Wnt/beta-catenin; Porcupine

References

Madan B, et al. Wnt addiction of genetically defined cancers reversed by PORCN inhibition. Oncogene. 2015 Aug 10. doi: 10.1038/onc.2015.280.