TargetMol

RMC-6272

Product Code:
 
TAR-T39959
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T39959-5mg5mg£1,564.00
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Quantity:
TAR-T39959-10mg10mg£1,934.00
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This product comes from: United States.
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Further Information

Bioactivity:
RMC-6272 (RM-006) is a bi-steric mTORC1 -selective inhibitor. RMC-6272 exhibits potent and selective (> 10-fold) inhibition of mTORC1 over mTORC2. RMC-6272 shows improved inhibition of mTORC1 in comparison to Rapamycin, and induces more cell death in TSC2 null tumors.
CAS:
2382769-46-0
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0

References

Heng Du, et al. Bi-steric mTORC1-selective inhibitors demonstrate improved potency and efficacy in tumors with mTORC1 hyperactivation [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2021; 2021 Apr 10-15 and May 17-21. Philadelphia (PA): AACR; Cancer Res 2021;81(13_Suppl):Abstract nr 1026.