TargetMol

MY33-3

Product Code:
 
TAR-T39677
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T39677-5mg5mg£284.00
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Further Information

Bioactivity:
MY33-3 is a potent and selective inhibitor of receptor protein tyrosine phosphatase (RPTP)β/ζ , with an IC 50 of ~0.1 μM. MY33-3 also inhibits PTP-1B ( IC 50 ~0.7 μM). MY33-3 can reduce ethanol consumption and alleviate Sevoflurane-induced neuroinflammation and cognitive dysfunction.
CAS:
2204280-41-9
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0

References

Fern?ndez-Calle R, et, al. Pharmacological inhibition of Receptor Protein Tyrosine Phosphatase ?/? (PTPRZ1) modulates behavioral responses to ethanol. Neuropharmacology. 2018 Jul 15;137:86-95. Mao S, et, al. Pleiotrophin Potentiates Sevoflurane Anesthesia-induced Learning Deficits in Mice. J Mol Neurosci. 2022 Jan;72(1):48-55. Fern?ndez-Calle R, et, al. Role of RPTP?/? in neuroinflammation and microglia-neuron communication. Sci Rep. 2020 Nov 20;10(1):20259.