TargetMol

DS86760016

Product Code:
 
TAR-T39296
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T39296-5mg5mg£736.00
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Further Information

Bioactivity:
DS86760016 is a potent leucyl-tRNA synthetase (LeuRS) inhibitor with activity against multidrug-resistant (MDR) Gram-negative bacteria, such as Escherichia coli , Klebsiella pneumoniae , and Pseudomonas aeruginosa . DS86760016 inhibits LeuRS enzymes from Escherichia coli , Pseudomonas aeruginosa , and Acinetobacter baumannii , with IC 50 s of 0.38, 0.62, and 0.16 μM, respectively.
CAS:
1853176-89-2
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0

References

Kumar M, et al. DS86760016, a Leucyl-tRNA Synthetase Inhibitor with Activity against Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2019;63(4):e02122-18. Published 2019 Mar 27. Purnapatre KP, et al. In Vitro and In Vivo Activities of DS86760016, a Novel Leucyl-tRNA Synthetase Inhibitor for Gram-Negative Pathogens. Antimicrob Agents Chemother. 2018;62(4):e01987-17. Published 2018 Mar 27.