TargetMol

Punicalagin

Product Code:
 
TAR-T3921
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T3921-20mg20mg£175.00
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Quantity:
TAR-T3921-1mL1 mL * 10 mM (in DMSO)£183.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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TAR-T3921-50mg50mg£230.00
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This product comes from: United States.
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Further Information

Bioactivity:
Punicalagin is a major ellagitannin found in pomegranates that is reported to produce antioxidant, anti-inflammatory, and anticancer effects. It has been shown to prevent high-fat diet-induced obesity-associated accumulation of cardiac triglyceride and cholesterol, as well as myocardial damage, via AMPK-mediated modulation of mitochondria and phase II enzymes.
CAS:
65995-63-3
Formula:
C48H28O30
Molecular Weight:
1084.722
Pathway:
Microbiology/Virology
Purity:
0.997
SMILES:
OC1O[C@@H]2COC(=O)c3cc(O)c(O)c(O)c3-c3c(O)c(O)c4oc(=O)c5c(c(O)c(O)c6oc(=O)c3c4c56)-c3c(O)c(O)c(O)cc3C(=O)O[C@H]2[C@@H]2OC(=O)c3cc(O)c(O)c(O)c3-c3c(O)c(O)c(O)cc3C(=O)O[C@@H]12
Target:
SARS-CoV; HBV

References

Seeram, N.P., et al. In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice. J. Nutr. Biochem. 16(6), 360-367 (2005). Luo Z, Kuang X, Zhou Q, et al. Inhibitory effects of baicalein against herpes simplex virus type 1. Acta Pharmaceutica Sinica B. 2020, 10(12): 2323-2338 Luo Z, Kuang X, Zhou Q, et al. Inhibitory effects of baicalein against herpes simplex virus type 1[J]. Acta Pharmaceutica Sinica B. 2020, 10(12): 2323-2338 Cao, K.,Pu, W.,Dong, Z., et al. Punicalagin, an active component in pomegranate, ameliorates cardiac mitochondrial impairment in obese rats via AMPK activation. Sci. Rep. 5, 14014 (2015).