TargetMol

BMS-986143

Product Code:
 
TAR-T39129
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T39129-5mg5mg£850.00
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Quantity:
TAR-T39129-50mg50mg£1,661.00
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Quantity:
TAR-T39129-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
BMS-986143 is an orally active, reversible BTK inhibitor with an IC 50 of 0.26 nM. BMS-986143 also inhibits TEC, BLK, BMX, TXK FGR, YES1, ITK with IC 50 s of 3 nM, 5 nM, 7 nM, 10 nM, 15 nM,19 nM, 21 nM, respectively. BMS-986143 can be used for the research of autoimmune diseases.
CAS:
1643372-95-5
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0

References

Anurag S Srivastava, et al. Driving Potency with Rotationally Stable Atropisomers: Discovery of Pyridopyrimidinedione-Carbazole Inhibitors of BTK. ACS Med Chem Lett. 2020 Sep 16;11(11):2195-2203.