TargetMol

D-threo-PPMP

Product Code:
 
TAR-T38822
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38822-5mg5mg£850.00
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This product comes from: United States.
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Further Information

Bioactivity:
D-threo-PPMP is a potent inhibitor of glucosylceramide (GlcCer) synthase . D-threo-PPMP can block karyokinesis and reduce cyst production.
CAS:
139889-53-5
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0

References

Hernandez Y. Novel role of sphingolipid synthesis genes in regulating giardial encystation. Infect Immun. 2008 Jul;76(7):2939-49. Gouaz? V, et, al. Glucosylceramide synthase blockade down-regulates P-glycoprotein and resensitizes multidrug-resistant breast cancer cells to anticancer drugs. Cancer Res. 2005 May 1;65(9):3861-7. Wu X, et, al. Liquid chromatography method for quantifying D-threo-1-phenyl-2-palmitoylamino-3-morpholino-1-propanol (D-threo-PPMP) in mouse plasma and liver. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Jun 6;837(1-2):44-8.