TargetMol

BM-1197

Product Code:
 
TAR-T38810
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38810-5mg5mg£850.00
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Further Information

Bioactivity:
BM-1197 is a potent and selective inhibitor of dual Bcl-2/Bcl-xL , with IC 50 s of 3.5 nM and 5.2 nM for Bcl-2 and Bcl-xL, respectively. BM-1197 exhibits antitumor effects both in vitro and in vivo.
CAS:
1391107-89-3
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0

References

Sun YL, et, al. A novel Bcl-2 inhibitor, BM-1197, induces apoptosis in malignant lymphoma cells through the endogenous apoptotic pathway. BMC Cancer. 2019 Dec 31; 20(1):1. Bai L, et, al. BM-1197: a novel and specific Bcl-2/Bcl-xL inhibitor inducing complete and long-lasting tumor regression in vivo. PLoS One. 2014 Jun 5; 9(6): e99404.