TargetMol

AP 811

Product Code:
 
TAR-T38641
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38641-5mg5mg£551.00
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Further Information

Bioactivity:
AP 811 is a selective atrial natriuretic peptide clearance receptor (APN-CR, NPR3) antagonist ( K i =0.48 nM). AP 811 displays >20,000-fold selectivity for NPR3 over NPR1. AP 811 abolishes ANP-induced pump stimulation.
CAS:
124833-45-0
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0

References

Veale CA, et al. The discovery of non-basic atrial natriuretic peptide clearance receptor antagonists. Part 1. Bioorg Med Chem Lett. 2000;10(17):1949-1952. William M, et al. Natriuretic peptides stimulate the cardiac sodium pump via NPR-C-coupled NOS activation. Am J Physiol Cell Physiol. 2008;294(4):C1067-C1073.