TargetMol

Eudesmin

Product Code:
 
TAR-T3836
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T3836-1mg1mg£220.00
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TAR-T3836-5mg5mg£440.00
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TAR-T3836-1mL1 mL * 10 mM (in DMSO)£448.00
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TAR-T3836-10mg10mg£613.00
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TAR-T3836-25mg25mg£922.00
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TAR-T3836-50mg50mg£1,219.00
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TAR-T3836-100mg100mg£1,621.00
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This product comes from: United States.
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Further Information

Bioactivity:
Eudesmin shows antiinflammatory, neuritogenic, anticonvulsant and sedative effects, the mechanism of eudesmin may be related to up-regulation of GABAA and GAD65 expressions, and anti-apoptosis of neuron the in brain.50 microM (+)-eudesmin can induce neurite outgrowth and enhance nerve growth factor (NGF)-mediated neurite outgrowth from PC12 cells by stimulating up-stream MAPK, PKC and PKA pathways.
CAS:
526-06-7
Formula:
C22H26O6
Molecular Weight:
386.444
Pathway:
PI3K/Akt/mTOR signaling; MAPK
Purity:
0.9992
SMILES:
COc1ccc(cc1OC)[C@@H]1OC[C@@H]2[C@H]1CO[C@H]2c1ccc(OC)c(OC)c1
Target:
MAPK; S6 Kinase

References

Yang C, Xu H, Yang D, et al.A renal YY1-KIM1-DR5 axis regulates the progression of acute kidney injury.Nature Communications.2023, 14(1): 4261. Cho J Y , Yoo E S , Baik K U , et al. Eudesmin inhibits tumor necrosis factor-alpha production and T cell proliferation[J]. Archives of Pharmacal Research, 1999, 22(4):348-353.