TargetMol

Reduced Haloperidol

Product Code:
 
TAR-T37167
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T37167-5mg5mg£129.00
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TAR-T37167-10mg10mg£185.00
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TAR-T37167-25mg25mg£329.00
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TAR-T37167-50mg50mg£560.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Reduced haloperidol is an active metabolite of haloperidol . It is formed via reduction of haloperidol by ketone reductase. Reduced haloperidol inhibits radioligand binding to sigma-1 and dopamine D2 receptors (Kis = 1.4 and 31 nM, respectively) and stimulates brain-derived neurotrophic factor (BDNF) secretion from CCF-SSTG1 and U87MG astrocytic glial cells. It also inhibits norepinephrine, dopamine, and serotonin (5-HT) reuptake (Kis = 21, 25, and 33 μM, respectively, in COS-7 cells expressing the human transporters). Reduced haloperidol (0.5 mg/kg) increases latency to paw withdrawal in mouse models of capsaicin- but not force-induced mechanical hypersensitivity.
CAS:
34104-67-1
Formula:
C21H25ClFNO2
Molecular Weight:
377.9
Purity:
0.98
SMILES:
OC1(CCN(CCCC(C2=CC=C(F)C=C2)O)CC1)C3=CC=C(Cl)C=C3