TargetMol

Tie2 Inhibitor 7

Product Code:
 
TAR-T36718
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T36718-5mg5mg£850.00
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Quantity:
TAR-T36718-50mg50mg£1,661.00
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Quantity:
TAR-T36718-100mg100mg£2,079.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Tie2 Inhibitor 7 blocks Tie2 kinase activity with a Ki value of 1.3 μM.. It has been shown to inhibit angiopoietin 1-induced Tie2 autophosphorylation and downstream signaling with an IC50 value of 0.3 μM. This compound can prevent endothelial cell tube formation and aberrant vessel growth in a rat model of Matrigel-induced choroidal neovascularization.
CAS:
1020412-97-8
Formula:
C31H35N3O5
Molecular Weight:
529.637
Purity:
0.98
SMILES:
C[C@H](NC(=O)CN(Cc1ccc(cc1)-c1cncc(c1)C(O)=O)C(=O)Oc1ccc(C)cc1)C1CCCCC1