TargetMol

CTA 056

Product Code:
 
TAR-T35569
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T35569-5mg5mg£850.00
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TAR-T35569-50mg50mg£1,661.00
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Quantity:
TAR-T35569-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Interleukin-2-inducible T-cell kinase (ITK) inhibitor (IC50 values are 0.1, 0.4 and 5 μM for ITK, BTK and ETK, respectively). Inhibits growth of cancer cells expressing ITK, including MOLT-4 and Jurkat cells in vitro. Induces apoptosis in Jurkat cells. Inhibits MOLT-4 xenograft tumor growth in mice.
CAS:
1265822-30-7
Formula:
C35H34N6O
Molecular Weight:
554.68
Purity:
0.98
SMILES:
O=C2C(CC7=CC=CC=C7)=NC1=CC3=C(N=C(C5=CC=C(C6=CC=NC=C6)C=C5)N3CCCN4CCCCC4)C=C1N2

References

Guo et al (2012) Molecular characteristics of CTA056, a novel interleukin-2-inducible T-cell kinase inhibitor that selectively targets malignant T cells and modulates oncomirs. Mol.Pharmacol. 82 938 PMID:22899868