TargetMol

ZYZ-803

Product Code:
 
TAR-T35323
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T35323-5mg5mg£850.00
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TAR-T35323-50mg50mg£1,661.00
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Quantity:
TAR-T35323-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
ZYZ-803 is a slow H2S-NO-releasing hybrid, attenuating cardiac dysfunction after heart failure.
CAS:
2088043-51-8
Formula:
C20H23N3O6S
Molecular Weight:
433.48
Purity:
0.98
SMILES:
CC(C)(C)OC(=O)N[C@@H](CSCC#C)C(=O)OCc1c(no[n+]1[O-])-c1ccccc1

References

Wu D, Hu Q, Xiong Y, Zhu D, Mao Y, Zhu YZ. Novel H(2)S-NO hybrid molecule (ZYZ-803) promoted synergistic effects against heart failure. Redox Biol. 2018 May;15:243-252. doi: 10.1016/j.redox.2017.11.020. Epub 2017 Dec 14. PubMed PMID: 29288927; PubMed Central PMCID: PMC5975222. Hu Q, Wu D, Ma F, Yang S, Tan B, Xin H, Gu X, Chen X, Chen S, Mao Y, Zhu YZ. Novel Angiogenic Activity and Molecular Mechanisms of ZYZ-803, a Slow-Releasing Hydrogen Sulfide-Nitric Oxide Hybrid Molecule. Antioxid Redox Signal. 2016 Sep 10;25(8):498-514. doi: 10.1089/ars.2015.6607. Epub 2016 Jun 29. PubMed PMID: 27174595. Wu D, Hu Q, Ma F, Zhu YZ. Vasorelaxant Effect of a New Hydrogen Sulfide-Nitric Oxide Conjugated Donor in Isolated Rat Aortic Rings through cGMP Pathway. Oxid Med Cell Longev. 2016;2016:7075682. doi: 10.1155/2016/7075682. Epub 2015 Nov 9. PubMed PMID: 26635911; PubMed Central PMCID: PMC4655279.