TargetMol

TPT-172 HCl (R33)

Product Code:
 
TAR-T34911
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T34911-5mg5mg£850.00
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TAR-T34911-50mg50mg£1,661.00
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TAR-T34911-100mg100mg£2,079.00
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Further Information

Bioactivity:
TPT-172, also known as R33 (described in Mecozzi et al' s paper), is a thiophene thiourea derivative with molecule weight 172 in free base form. There is no formal name yet, we temporally call this molecule as TPT-172. Please also see similar products: TPT-197; TPT-260; TPT-172.
CAS:
32415-42-2
Formula:
C6H9ClN2S2
Molecular Weight:
208.72
Purity:
0.98
SMILES:
Cl.NC(=N)SCc1cccs1

References

Mecozzi VJ, Berman DE, Simoes S, Vetanovetz C, Awal MR, Patel VM, Schneider RT, Petsko GA, Ringe D, Small SA. Pharmacological chaperones stabilize retromer to limit APP processing. Nat Chem Biol. 2014 Jun;10(6):443-9. doi: 10.1038/nchembio.1508. Epub 2014 Apr 20. PubMed PMID: 24747528.