TargetMol

Rosmarinine

Product Code:
 
TAR-T34391
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T34391-5mg5mg£850.00
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Further Information

Bioactivity:
Rosmarinine is a non-toxic pyrrolizidine alkaloid.
CAS:
520-65-0
Formula:
C18H27NO6
Molecular Weight:
353.415
Purity:
0.98
SMILES:
[H][C@]12CCN3C[C@@H](O)[C@]([H])(COC(=O)[C@](C)(O)[C@H](C)CC(=CC)C(=O)O1)[C@]23[H]

References

Styles J, Ashby J, Mattocks AR. Evaluation in vitro of several pyrrolizidine alkaloid carcinogens: observations on the essential pyrrolic nucleus. Carcinogenesis. 1980 Feb;1(2):161-4. PubMed PMID: 22282996. Nieto-Alvarez DA, Calder?n JS, Mancilla T. Synthesis of (1R,2R,7R,7aS)-1-hydroxymethyl-2,3,5,6,7,7a-hexahydropyrrolizidine-1,2,7-triol from rosmarinine degradation. Nat Prod Res. 2003 Jan;17(1):33-6. PubMed PMID: 12674140. Castells E, Mulder PP, P?rez-Trujillo M. Diversity of pyrrolizidine alkaloids in native and invasive Senecio pterophorus (Asteraceae): implications for toxicity. Phytochemistry. 2014 Dec;108:137-46. doi: 10.1016/j.phytochem.2014.09.006. Epub 2014 Sep 27. PubMed PMID: 25269662. Z?ndorf I, Wiedenfeld H, R?der E, Dingermann T. Generation and characterization of monoclonal antibodies against the pyrrolizidine alkaloid retrorsine. Planta Med. 1998 Apr;64(3):259-63. PubMed PMID: 9581524.