Pulchellin

Product Code:

TAR-T34191

Product Group:

Inhibitors and Activators

Supplier:

TargetMol

Regulatory Status:

RUO

Shipping:

cool pack

Storage:

-20℃

No additional charges, what you see is what you pay! *

Code	Size	Price

TAR-T34191-5mg

5mg

£850.00

Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.

Quantity:

Prices exclude any Taxes / VAT

How to order with us Contact us

Further Information

Bioactivity:

Pulchellin is a type-2 Ribosome Inactivating Protein (RIP), whose action mechanism proposed would be initiate by B-chain binding on glycoconjugate onto the cell surface (lectinic chain). pulchellin isoforms toxicity is the interaction between B-chain lectinic and the glycosyl residues on cell surface. pulchellin A chain is a novel of selective immunotoxin cytotoxicity.

CAS:

6754-35-4

Formula:

C15H22O4

Molecular Weight:

266.337

Purity:

0.98

SMILES:

C[C@@H]1C[C@@H]2OC(=O)C(=C)[C@H]2C[C@]2(C)[C@H](O)C[C@H](O)C12

Documents

References

Ivanova V, Trendafilova A, Todorova M, Danova K, Dimitrov D. Phytochemical Profile of Inula britannica from Bulgaria. Nat Prod Commun. 2017 Feb;12(2):153-154. PubMed PMID: 30428197. Sadraeian M, Guimar?es FEG, Ara?jo APU, Worthylake DK, LeCour LJ, Pincus SH. Selective cytotoxicity of a novel immunotoxin based on pulchellin A chain for cells expressing HIV envelope. Sci Rep. 2017 Aug 8;7(1):7579. doi: 10.1038/s41598-017-08037-3. PubMed PMID: 28790381; PubMed Central PMCID: PMC5548917. Huang H, Niu J, Wang F, Hu L, Yu Q. A natural compound derivative P-13 inhibits STAT3 signaling by covalently inhibiting Janus kinase 2. Invest New Drugs. 2018 Aug 3. doi: 10.1007/s10637-018-0637-2. [Epub ahead of print] PubMed PMID: 30073465. Xiao H, Rao Ravu R, Tekwani BL, Li W, Liu WB, Jacob MR, Khan SI, Cai X, Peng CY, Khan IA, Li XC, Wang W. Biological evaluation of phytoconstituents from Polygonum hydropiper. Nat Prod Res. 2017 Sep;31(17):2053-2057. doi: 10.1080/14786419.2016.1269094. Epub 2016 Dec 21. PubMed PMID: 28000515.