TargetMol

Orotirelin

Product Code:
 
TAR-T33824
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T33824-1mg1mg£278.00
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TAR-T33824-5mg5mg£586.00
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TAR-T33824-10mg10mg£804.00
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TAR-T33824-25mg25mg£1,171.00
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Quantity:
TAR-T33824-50mg50mg£1,556.00
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Quantity:
TAR-T33824-100mg100mg£2,079.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Orotirelin, a Thyrotropin-releasing hormone analog with possible therapeutic application in sleep disorders can increase dopamine release from rat brain.
CAS:
62305-86-6
Formula:
C16H19N7O5
Molecular Weight:
389.372
Purity:
0.98
SMILES:
NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)c1cc(=O)[nH]c(=O)[nH]1

References

Fone KC, et al. Involvement of catecholaminergic neurones and alpha-adrenoceptors in the wet-dog shake and forepaw licking behaviour produced by the intrathecal injection of an analogue of thyrotrophin-releasing hormone (CG 3509). Neuropharmacology. 1987 Aug;26(8):1147-55. Sharp T, et al. Analeptic effects of centrally injected TRH and analogues of TRH in the pentobarbitone-anaesthetized rat. Neuropharmacology. 1984 Mar;23(3):339-48. Fone KC, et al. Involvement of 5-HT2 receptors in the behaviours produced by intrathecal administration of selected 5-HT agonists and the TRH analogue (CG 3509) to rats. Br J Pharmacol. 1989 Mar;96(3):599-608. Fone KC, et al. Spinal effects of chronic intrathecal administration of the thyrotrophin-releasing hormone analogue (CG 3509) in rats. Brain Res. 1988 Jul 5;455(1):157-61.