TargetMol

Opc 8490

Product Code:
 
TAR-T33807
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T33807-5mg5mg£850.00
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TAR-T33807-50mg50mg£1,661.00
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Quantity:
TAR-T33807-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Opc 8490 is a positive inotropic agent.
CAS:
123941-50-4
Formula:
C30H35N3O10
Molecular Weight:
597.621
Purity:
0.98
SMILES:
OC(=O)CC(O)(CC(O)=O)C(O)=O.O=C(CCCN1CCN(CC1)C(=O)c1ccc2NC(=O)CCc2c1)c1ccccc1

References

Furukawa Y, Akahane K, Haniuda M, Chiba S. Positive inotropic and negative chronotropic effects of OPC-8490, a newly developed cardiotonic, in isolated, blood-perfused canine heart preparations. Jpn Heart J. 1989 May;30(3):387-98. PubMed PMID: 2552190. Endoh M, Satoh H, Norota I, Hirano K, Hosokawa T. Subcellular mechanism of the positive inotropic effect of a new quinolinone derivative OPC-8490 on the dog ventricular myocardium. Heart Vessels. 1991;6(3):158-67. PubMed PMID: 1655692. Kurachi Y, Asano Y, Ito H, Sugimoto T. Voltage-dependent inhibition of the delayed outward potassium current by OPC-8490, a novel positive inotropic agent, in isolated atrial myocytes of guinea-pig heart. Naunyn Schmiedebergs Arch Pharmacol. 1990 Apr;341(4):324-30. PubMed PMID: 1692107. Focaccio A, Peeters G, Movsesian M, Roden R, Eki Y, Krall J, Bristow MR. Mechanism of action of OPC-8490 in human ventricular myocardium. Circulation. 1996 Feb 15;93(4):817-25. PubMed PMID: 8641012.