TargetMol

Oleoyl proline

Product Code:
 
TAR-T33789
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T33789-5mg5mg£304.00
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TAR-T33789-10mg10mg£454.00
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TAR-T33789-25mg25mg£784.00
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This product comes from: United States.
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Further Information

Bioactivity:
Oleoyl proline is an N-acyl amine that can be detected in bovine brain extracts and D. melanogaster larvae using mass spectrometry. In a preclinical model of pain, mice lacking fatty acid amide hydrolase (FAAH KO) had decreased N-oleoyl proline levels in the lumbar spinal cord after capsaicin administration (1 ?g/10 ?l).
CAS:
107432-37-1
Formula:
C23H41NO3
Molecular Weight:
379.585
Purity:
0.98
SMILES:
CCCCCCCCC=C/CCCCCCCC(=O)N1CCC[C@H]1C(O)=O

References

Cabrera MP, Baldissera G, Silva-Gon?alves Lda C, Souza BM, Riske KA, Palma MS, Ruggiero JR, Arcisio-Miranda M. Combining experimental evidence and molecular dynamic simulations to understand the mechanism of action of the antimicrobial octapeptide jelleine-I. Biochemistry. 2014 Jul 29;53(29):4857-68. doi: 10.1021/bi5003585. Epub 2014 Jul 14. PubMed PMID: 24971729. Nadeau VG, Deber CM. Loop sequence dictates the secondary structure of a human membrane protein hairpin. Biochemistry. 2013 Apr 9;52(14):2419-26. doi: 10.1021/bi400187w. Epub 2013 Mar 29. PubMed PMID: 23488803. Hong K, Zhao G, Hong Z, Sun Z, Yang Y, Clifford PS, Davis MJ, Meininger GA, Hill MA. Mechanical activation of angiotensin II type 1 receptors causes actin remodelling and myogenic responsiveness in skeletal muscle arterioles. J Physiol. 2016 Dec 1;594(23):7027-7047. doi: 10.1113/JP272834. Epub 2016 Oct 13. PubMed PMID: 27531064; PubMed Central PMCID: PMC5134373. Kariyazono H, Nadai R, Miyajima R, Takechi-Haraya Y, Baba T, Shigenaga A, Okuhira K, Otaka A, Saito H. Formation of stable nanodiscs by bihelical apolipoprotein A-I mimetic peptide. J Pept Sci. 2016 Feb;22(2):116-22. doi: 10.1002/psc.2847. Epub 2016 Jan 19. PubMed PMID: 26780967.