TargetMol

MK789

Product Code:
 
TAR-T33441
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T33441-5mg5mg£850.00
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Quantity:
TAR-T33441-50mg50mg£1,661.00
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Quantity:
TAR-T33441-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
MK-789 is an inhibitor of dehydropeptidase I. MK-789 and MK-791 alter the renal excretion of N-formimidoyl thienamycin from glomerular filtration plus tubular secretion to glomerular filtration only, possibly by competitively inhibiting the penetration of N-formimidoyl thienamycin into the proximal tubular cells.
CAS:
85394-14-5
Formula:
C14H23NO3
Molecular Weight:
253.342
Purity:
0.98
SMILES:
CCCCCC=C(NC(=O)C1CC1(C)C)C(O)=O

References

Norrby SR, Alestig K, Bj?rneg?rd B, Burman LA, Ferber F, Huber JL, Jones KH, Kahan FM, Kahan JS, Kropp H, Meisinger MA, Sundelof JG. Urinary recovery of N-formimidoyl thienamycin (MK0787) as affected by coadministration of N-formimidoyl thienamycin dehydropeptidase inhibitors. Antimicrob Agents Chemother. 1983 Feb;23(2):300-7. PubMed PMID: 6573157; PubMed Central PMCID: PMC186041.