TargetMol

MK 410

Product Code:
 
TAR-T33417
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T33417-5mg5mg£850.00
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TAR-T33417-50mg50mg£1,661.00
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Quantity:
TAR-T33417-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
MK 410 is an indomethacin analogue and anti-inflammatory agent that induces changes in the immune system by inhibiting plasma neutral protease activity.
CAS:
40738-05-4
Formula:
C21H23NO3S
Molecular Weight:
369.48
Purity:
0.98
SMILES:
COc1ccc2n(Cc3ccc(SC)cc3)c(C)c(C(C)C(O)=O)c2c1

References

Lassmann G, Curtis J, Liermann B, Mason RP, Eling TE. ESR studies on reactivity of protein-derived tyrosyl radicals formed by prostaglandin H synthase and ribonucleotide reductase. Arch Biochem Biophys. 1993 Jan;300(1):132-6. PubMed PMID: 8380961. Markey CM, Alward A, Weller PE, Marnett LJ. Quantitative studies of hydroperoxide reduction by prostaglandin H synthase. Reducing substrate specificity and the relationship of peroxidase to cyclooxygenase activities. J Biol Chem. 1987 May 5;262(13):6266-79. PubMed PMID: 3106353. Hart DA, Mannerfeldt J, Babins E. Treatment of mice with indomethacin leads to the appearance of a 125,000 dalton plasma protein with the characteristics of an acute phase reactant. J Clin Lab Immunol. 1987 Jun;23(2):83-90. PubMed PMID: 2442392. Van Dyke K, Peden D, Van Dyke C, Jones G, Castranova V, Ma J. Inhibition by nonsteroidal antiinflammatory drugs of luminol-dependent human-granulocyte chemiluminescence and [3H]FMLP binding. Effect of sulindac sulfide, indomethacin metabolite, and optical enantiomers (+) and (-) MK830. Inflammation. 1982 Mar;6(1):113-25. PubMed PMID: 7085041.