TargetMol

Methyl-d9-choline

Product Code:
 
TAR-T33348
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T33348-5mg5mg£850.00
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Further Information

Bioactivity:
Methyl -D9- choline is an isotopically labeled choline tracer.
CAS:
50673-41-1
Formula:
C5H14NO
Molecular Weight:
113.227
Purity:
0.98
SMILES:
[2H]C([2H])([2H])[N+](CCO)(C([2H])([2H])[2H])C([2H])([2H])[2H]

References

Yan J, Ginsberg SD, Powers B, Alldred MJ, Saltzman A, Strupp BJ, Caudill MA. Maternal choline supplementation programs greater activity of the phosphatidylethanolamine N-methyltransferase (PEMT) pathway in adult Ts65Dn trisomic mice. FASEB J. 2014 Oct;28(10):4312-23. doi: 10.1096/fj.14-251736. Epub 2014 Jun 24. PubMed PMID: 24963152; PubMed Central PMCID: PMC4202107. Dushianthan A, Goss V, Cusack R, Grocott MP, Postle AD. Altered molecular specificity of surfactant phosphatidycholine synthesis in patients with acute respiratory distress syndrome. Respir Res. 2014 Nov 7;15:128. doi: 10.1186/s12931-014-0128-8. PubMed PMID: 25378080; PubMed Central PMCID: PMC4226855. Dushianthan A, Cusack R, Grocott MPW, Postle AD. Abnormal liver phosphatidylcholine synthesis revealed in patients with acute respiratory distress syndrome. J Lipid Res. 2018 May 1. pii: jlr.P085050. doi: 10.1194/jlr.P085050. [Epub ahead of print] PubMed PMID: 29716960. Davenport C, Yan J, Taesuwan S, Shields K, West AA, Jiang X, Perry CA, Malysheva OV, Stabler SP, Allen RH, Caudill MA. Choline intakes exceeding recommendations during human lactation improve breast milk choline content by increasing PEMT pathway metabolites. J Nutr Biochem. 2015 Sep;26(9):903-11. doi: 10.1016/j.jnutbio.2015.03.004. Epub 2015 Apr 15. PubMed PMID: 26025328.