TargetMol

Meliantriol

Product Code:
 
TAR-T33279
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T33279-5mg5mg£850.00
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This product comes from: United States.
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Further Information

Bioactivity:
Meliantriol is an active compound in Azadirachta indica (Neem). It can bind to PBP2A and PVL toxin with the binding energies of -6.02 kcal/mol and -8.94 kcal/mol, respectively.
CAS:
25278-95-9
Formula:
C30H50O5
Molecular Weight:
490.725
Purity:
0.98
SMILES:
[H][C@]12CC[C@@]3(C)[C@@H](CC[C@]3(C)C1=CC[C@@]1([H])C(C)(C)[C@@H](O)CC[C@]21C)[C@@H]1C[C@@H](O[C@H]1O)[C@H](O)C(C)(C)O

References

Sarmento UC, Miguita CH, Almeida LH, Gaban CR, Silva LM, Souza AS, Garcez WS, Garcez FR. Larvicidal efficacies of plants from Midwestern Brazil: melianodiol from Guarea kunthiana as a potential biopesticide against Aedes aegypti. Mem Inst Oswaldo Cruz. 2016 Jun 20;0:0. doi: 10.1590/0074-02760160134. PubMed PMID: 27333366; PubMed Central PMCID: PMC4957500. Hummel HE, Langner SS, Leithold G, Schmutterer H. NEEM: UNUSUALLY VERSATILE PLANT GENUS AZADIRACHTA WITH MANY USEFUL AND SO FAR INSUFFICIENTLY EXPLOITED PROPERTIES FOR AGRICULTURE, MEDICINE, AND INDUSTRY. Commun Agric Appl Biol Sci. 2014;79(2):211-28. Review. PubMed PMID: 26084100. Skariyachan S, Krishnan RS, Siddapa SB, Salian C, Bora P, Sebastian D. Computer aided screening and evaluation of herbal therapeutics against MRSA infections. Bioinformation. 2011;7(5):222-33. Epub 2011 Oct 31. PubMed PMID: 22125390; PubMed Central PMCID: PMC3218416. Miguita CH, Barbosa Cda S, Hamerski L, Sarmento UC, Nascimento JN, Garcez WS, Garcez FR. 3?-O-tigloylmelianol from Guarea kunthiana: a new potential agent to control Rhipicephalus (Boophilus) microplus, a cattle tick of veterinary significance. Molecules. 2014 Dec 23;20(1):111-26. doi: 10.3390/molecules20010111. PubMed PMID: 25546624.