TargetMol

MDL-72274 HCl

Product Code:
 
TAR-T33265
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T33265-5mg5mg£850.00
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TAR-T33265-50mg50mg£1,661.00
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Quantity:
TAR-T33265-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
MDL-72274 HCl is a selective and effective inhibitor of SSAO for the treatment of Parkinson's disease.
CAS:
85278-24-6
Formula:
C9H11Cl2N
Molecular Weight:
204.09
Purity:
0.98
SMILES:
Cl.NCC(=CCl)c1ccccc1

References

Langford SD, Trent MB, Boor PJ. Semicarbazide-sensitive amine oxidase and extracellular matrix deposition by smooth-muscle cells. Cardiovasc Toxicol. 2002;2(2):141-50. PubMed PMID: 12271157. Holt A, Todd KG, Baker GB. The effects of chronic administration of inhibitors of flavin and quinone amine oxidases on imidazoline I(1) receptor density in rat whole brain. Ann N Y Acad Sci. 2003 Dec;1009:309-22. PubMed PMID: 15028605. Pirisino R, Ghelardini C, Banchelli G, Galeotti N, Raimondi L. Methylamine and benzylamine induced hypophagia in mice: modulation by semicarbazide-sensitive benzylamine oxidase inhibitors and aODN towards Kv1.1 channels. Br J Pharmacol. 2001 Oct;134(4):880-6. PubMed PMID: 11606329; PubMed Central PMCID: PMC1573009. Conklin DJ, Bhatnagar A, Cowley HR, Johnson GH, Wiechmann RJ, Sayre LM, Trent MB, Boor PJ. Acrolein generation stimulates hypercontraction in isolated human blood vessels. Toxicol Appl Pharmacol. 2006 Dec 15;217(3):277-88. Epub 2006 Sep 29. PubMed PMID: 17095030; PubMed Central PMCID: PMC3487162.