TargetMol

Linsidomine

Product Code:
 
TAR-T32770
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T32770-5mg5mg£850.00
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Further Information

Bioactivity:
Lincydomine is a smooth muscle relaxant, beneficial to the treatment of unstable angina pectoris, but also can open the respiratory tract of humans and guinea pigs.
CAS:
33876-97-0
Formula:
C6H10N4O2
Molecular Weight:
170.172
Purity:
0.98
SMILES:
[NH-]c1c[n+](no1)N1CCOCC1

References

1. Sutherland FC, de Jager AD, Swart KJ, Hundt HK, Scanes T, Hundt AF. Determination of linsidomine in human plasma by tandem LC-MS with ESI. J Pharm Biomed Anal. 2000 Apr;22(3):461-7. PubMed PMID: 10766363. 2. Spreux-Varoquaux O, Doll J, Dutot C, Grandjean N, Cordonnier P, Pays M, Andrieu J, Advenier C. Pharmacokinetics of molsidomine and its active metabolite, linsidomine, in patients with liver cirrhosis. Br J Clin Pharmacol. 1991 Sep;32(3):399-401. PubMed PMID: 1777378; PubMed Central PMCID: PMC1368538. 3. Stief CG, Holmquist F, Djamilian M, Krah H, Andersson KE, Jonas U. Preliminary results with the nitric oxide donor linsidomine chlorhydrate in the treatment of human erectile dysfunction. J Urol. 1992 Nov;148(5):1437-40. PubMed PMID: 1433545. 4. Prast H, Lamberti C, Fischer H, Tran MH, Philippu A. Nitric oxide influences the release of histamine and glutamate in the rat hypothalamus. Naunyn Schmiedebergs Arch Pharmacol. 1996 Dec;354(6):731-5. PubMed PMID: 8971733.