TargetMol

L 651580

Product Code:
 
TAR-T32454
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T32454-5mg5mg£850.00
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This product comes from: United States.
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Further Information

Bioactivity:
L 651580 is a bioactive chemical.
CAS:
103335-44-0
Formula:
C21H31NO3
Molecular Weight:
345.483
Purity:
0.98
SMILES:
[H][C@@]12CC[C@H](C(=O)OC)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])N(C)C(=O)C=C[C@]12C

References

1. Lu Q, Chen WY, Zhu ZY, Chen J, Xu YC, Kaewpet M, Rukachaisirikul V, Chen LL, Shen X. L655,240, acting as a competitive BACE1 inhibitor, efficiently decreases ?-amyloid peptide production in HEK293-APPswe cells. Acta Pharmacol Sin. 2012 Dec;33(12):1459-68. doi: 10.1038/aps.2012.74. Epub 2012 Jul 30. PubMed PMID: 22842730; PubMed Central PMCID: PMC4001842. 2. Weinberg ML, Moreira E, Weinberg J. Arachidonic acid products-mediated contraction induced by bradykinin in relaxed mesenteric arterial rings from Holtzman rats. Eur J Pharmacol. 1997 Feb 12;320(2-3):145-50. PubMed PMID: 9059847. 3. Campos AH, Calixto JB. Mechanisms involved in the contractile responses of kinins in rat portal vein rings: mediation by B1 and B2 receptors. J Pharmacol Exp Ther. 1994 Feb;268(2):902-9. PubMed PMID: 8114004. 4. Tardif M, Bergeron Y, Beauchamp D, Bergeron MG. Increased renal uptake of gentamicin in endotoxemic rats receiving concomitant thromboxane A2 antagonist therapy. Antimicrob Agents Chemother. 1993 Dec;37(12):2727-32. PubMed PMID: 8109943; PubMed Central PMCID: PMC192792.