TargetMol

Keto-anhydrokinamycin

Product Code:
 
TAR-T32385
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T32385-5mg5mg£850.00
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Further Information

Bioactivity:
Keto-anhydrokinamycin, as a keto-epoxide kinamycin intermediate, is isolated from Streptomyces murayamaensis.
CAS:
120796-25-0
Formula:
C18H10N2O6
Molecular Weight:
350.286
Purity:
0.98
SMILES:
[H][C@@]12O[C@]1(C)C(=O)c1c([C@@H]2O)c2c(C(=O)c3c(O)cccc3C2=O)n1C#N

References

1. Liang X, Van Parys M, Ding X, Zeng N, Bi L, Dorshort D, McKnight J, Milanowski D, Mao J, Chen Y, Ware JA, Dean B, Hop CE, Deng Y. Simultaneous determination of itraconazole, hydroxy itraconazole, keto itraconazole and N-desalkyl itraconazole concentration in human plasma using liquid chromatography with tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 May 1;1020:111-9. doi: 10.1016/j.jchromb.2016.03.039. Epub 2016 Mar 26. PubMed PMID: 27038403. 2. Liang X, Van Parys M, Ding X, Zeng N, Bi L, Dorshorst D, McKnight J, Milanowski D, Mao J, Chen Y, Ware JA, Dean B, Hop CECA, Deng Y. Corrigendum to "Simultaneous determination of itraconazole, hydroxy itraconazole, keto itraconazole and N-desalkyl itraconazole concentration in human plasma using liquid chromatography with tandem mass spectrometry" [J. Chromatogr. B 1020 (2016) 111-119]. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Sep 1;1029-1030:239. doi: 10.1016/j.jchromb.2016.06.023. Epub 2016 Jul 16. PubMed PMID: 27475407. 3. Mino Y, Naito T, Watanabe T, Yamada T, Yagi T, Yamada H, Kawakami J. Hydroxy-itraconazole pharmacokinetics is similar to that of itraconazole in immunocompromised patients receiving oral solution of itraconazole. Clin Chim Acta. 2013 Jan 16;415:128-32. doi: 10.1016/j.cca.2012.10.028. Epub 2012 Oct 23. PubMed PMID: 23089073. 4. Mino Y. [Optimization of Immunosuppression and the Prevention of Fungal Infection in Autoimmune Diseases]. Yakugaku Zasshi. 2015;135(10):1123-7. doi: 10.1248/yakushi.15-00193. Review. Japanese. PubMed PMID: 26423867.