TargetMol

Hexafluronium Bromide

Product Code:
 
TAR-T32066
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T32066-5mg5mg£850.00
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TAR-T32066-50mg50mg£1,661.00
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TAR-T32066-100mg100mg£2,079.00
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Further Information

Bioactivity:
Hexafluronium bromide is a neuromuscular blocker and nicotinic acetylcholine receptor antagonist used in anesthesiology to prolong and enhance the skeletal muscle relaxation of succinylcholine during surgery.
CAS:
317-52-2
Formula:
C36H42Br2N2
Molecular Weight:
662.554
Purity:
0.98
SMILES:
[Br-].[Br-].C[N+](C)(CCCCCC[N+](C)(C)C1c2ccccc2-c2ccccc12)C1c2ccccc2-c2ccccc12

References

1. Britton RM, Figueroa M. Hexafluorenium bromide: current status and a review. Anesth Analg. 1973 Jan-Feb;52(1):100-5. Review. PubMed PMID: 4567515. 2. Radnay PA, Badola RP, Dalsania A, El-Gaweet EI, Duncalf D. Prevention of suxamethonium-induced changes in serum potassium concentration by hexafluorenium. Is their combined use justified? Br J Anaesth. 1979 May;51(5):447-51. PubMed PMID: 444345. 3. Radnay PA, El-Gaweet ES, Novakovic M, Badola R, Cizmar S, Duncalf D. Prevention of succinylcholine induced hyperkalemia by neurolept anesthesia and hexafluorenium in anephric patients. Anaesthesist. 1981 Jul;30(7):334-7. PubMed PMID: 6455928. 4. Scaf AH, Langendijk JW. The desensitizing interaction of hexafluorenium with the cholinergic receptor in the diaphragm of the rat. Arch Int Pharmacodyn Ther. 1977 Feb;225(2):196-207. PubMed PMID: 849069.