TargetMol

PRE-084 hydrochloride

Product Code:
 
TAR-T3198L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3198L-5mg5mg£100.00
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TAR-T3198L-10mg10mg£118.00
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TAR-T3198L-1mL1 mL * 10 mM (in DMSO)£124.00
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TAR-T3198L-25mg25mg£169.00
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TAR-T3198L-50mg50mg£246.00
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TAR-T3198L-100mg100mg£383.00
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TAR-T3198L-200mg200mg£548.00
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Further Information

Bioactivity:
PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).
CAS:
75136-54-8
Formula:
C19H28ClNO3
Molecular Weight:
353.89
Pathway:
GPCR/G Protein
Purity:
0.9961
SMILES:
Cl.O=C(OCCN1CCOCC1)C1(CCCCC1)c1ccccc1
Target:
Sigma receptor

References

1. Peviani M, et al. Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084, in a mouse model of motor neuron disease not linked to SOD1 mutation. Neurobiol Dis. 2014 Feb;62:218-232. 2. Su TP, et al. Sigma compounds derived from phencyclidine: identification of PRE-084, a new, selective sigma ligand. J Pharmacol Exp Ther. 1991 Nov;259(2):543-550.