TargetMol

gamma-Lumicolchicine

Product Code:
 
TAR-T31906
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T31906-5mg5mg£850.00
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Further Information

Bioactivity:
gamma-Lumicolchicine is three, alpha, beta, and gamma isomers of ultraviolet degradation products of colchicine that lack many of the physiological actions of the parent; used as experimental control for colchicine actions.
CAS:
6901-14-0
Formula:
C22H25NO6
Molecular Weight:
399.443
Purity:
0.98
SMILES:
[H][C@@]12C=C(OC)C(=O)[C@]1([H])C1=C2c2c(CC[C@@H]1NC(C)=O)cc(OC)c(OC)c2OC

References

1. Bondi CD, McKeon RM, Bennett JM, Ignatius PF, Brydon L, Jockers R, Melan MA, Witt-Enderby PA. MT1 melatonin receptor internalization underlies melatonin-induced morphologic changes in Chinese hamster ovary cells and these processes are dependent on Gi proteins, MEK 1/2 and microtubule modulation. J Pineal Res. 2008 Apr;44(3):288-98. doi: 10.1111/j.1600-079X.2007.00525.x. PubMed PMID: 18339124. 2. Cacelli I, D'Auria M, Villani V. Theoretical Study of the Photochemical Isomerization of Colchicine. J Chem Theory Comput. 2007 Mar;3(2):649-56. doi: 10.1021/ct600306t. PubMed PMID: 26637043. 3. Morimoto T, Liu W, Woda C, Carattino MD, Wei Y, Hughey RP, Apodaca G, Satlin LM, Kleyman TR. Mechanism underlying flow stimulation of sodium absorption in the mammalian collecting duct. Am J Physiol Renal Physiol. 2006 Sep;291(3):F663-9. Epub 2006 Apr 25. PubMed PMID: 16638910. 4. Alali FQ, El-Elimat T, Li C, Qandil A, Alkofahi A, Tawaha K, Burgess JP, Nakanishi Y, Kroll DJ, Navarro HA, Falkinham JO 3rd, Wani MC, Oberlies NH. New colchicinoids from a native Jordanian meadow saffron, colchicum brachyphyllum: isolation of the first naturally occurring dextrorotatory colchicinoid. J Nat Prod. 2005 Feb;68(2):173-8. PubMed PMID: 15730238.