TargetMol

Formiminoglutamic acid

Product Code:
 
TAR-T31851
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T31851-5mg5mg£850.00
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TAR-T31851-50mg50mg£1,661.00
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Quantity:
TAR-T31851-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Formiminoglutamic acid is used to indicate folic acid deficiency and megaloblastic anemia of pregnancy with the measurement in the urine after oral administration of histidine.
CAS:
816-90-0
Formula:
C6H10N2O4
Molecular Weight:
174.156
Purity:
0.98
SMILES:
OC(=O)CC[C@H](NC=N)C(O)=O

References

1. Majumdar R, Yori A, Rush PW, Raymond K, Gavrilov D, Tortorelli S, Matern D, Rinaldo P, Feldman GL, Oglesbee D. Allelic spectrum of formiminotransferase-cyclodeaminase gene variants in individuals with formiminoglutamic aciduria. Mol Genet Genomic Med. 2017 Nov;5(6):795-799. doi: 10.1002/mgg3.333. Epub 2017 Sep 11. PubMed PMID: 29178637; PubMed Central PMCID: PMC5702579. 2. Su H, Sheng X, Liu Y. Exploring the substrate specificity and catalytic mechanism of imidazolonepropionase (HutI) from Bacillus subtilis. Phys Chem Chem Phys. 2016 Oct 12;18(40):27928-27938. PubMed PMID: 27711543. 3. Kyriakides M, Hardwick RN, Jin Z, Goedken MJ, Holmes E, Cherrington NJ, Coen M. Systems level metabolic phenotype of methotrexate administration in the context of non-alcoholic steatohepatitis in the rat. Toxicol Sci. 2014 Nov;142(1):105-16. doi: 10.1093/toxsci/kfu160. Epub 2014 Aug 21. PubMed PMID: 25145655; PubMed Central PMCID: PMC4226764. 4. Hai Y, Dugery RJ, Healy D, Christianson DW. Formiminoglutamase from Trypanosoma cruzi is an arginase-like manganese metalloenzyme. Biochemistry. 2013 Dec 23;52(51):9294-309. doi: 10.1021/bi401352h. Epub 2013 Nov 21. PubMed PMID: 24261485; PubMed Central PMCID: PMC3892564.