TargetMol

Fecnt F-18

Product Code:
 
TAR-T31758
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T31758-5mg5mgEnquire
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  • Further Information
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Further Information

Bioactivity:
[F-18] FECNT has been widely used to calculate dopamine transporter (DAT) occupancy rates in the brains of non-human primates and can distinguish DAT density differences between Parkinson's disease and healthy human controls.
CAS:
281667-89-8
Formula:
C17H21ClFNO2
Molecular Weight:
324.81
Purity:
0.98
SMILES:
[H][C@]12CC[C@]([H])([C@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)OC)N2CC[18F]

References

1. Honer M, Hengerer B, Blagoev M, Hintermann S, Waldmeier P, Schubiger PA, Ametamey SM. Comparison of [18F]FDOPA, [18F]FMT and [18F]FECNT for imaging dopaminergic neurotransmission in mice. Nucl Med Biol. 2006 Jul;33(5):607-14. Epub 2006 Jun 12. PubMed PMID: 16843835. 2. Votaw JR, Byas-Smith MG, Voll R, Halkar R, Goodman MM. Isoflurane alters the amount of dopamine transporter expressed on the plasma membrane in humans. Anesthesiology. 2004 Nov;101(5):1128-35. PubMed PMID: 15505448. 3. Votaw JR, Howell LL, Martarello L, Hoffman JM, Kilts CD, Lindsey KP, Goodman MM. Measurement of dopamine transporter occupancy for multiple injections of cocaine using a single injection of [F-18]FECNT. Synapse. 2002 Jun 15;44(4):203-10. PubMed PMID: 11984856.