TargetMol

Trovirdine hydrochloride

Product Code:
 
TAR-T3172L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T3172L-5mg5mg£850.00
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TAR-T3172L-50mg50mg£1,661.00
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TAR-T3172L-100mg100mg£2,079.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Trovirdine hydrochloride is a reverse transcriptase inhibitor.
CAS:
148311-89-1
Formula:
C13H14BrClN4S
Molecular Weight:
373.7
Purity:
0.98
SMILES:
Cl.Brc1ccc(NC(=S)NCCc2ccccn2)nc1

References

1. Gavriliu D, Fossey C, Ciurea A, Delbederi Z, Sugeac E, Ladur?e D, Schmidt S, Laumond G, Aubertin AM. Synthesis and anti-HIV activity of [d4U]-[trovirdine analogue] and [d4T]-[trovirdine analogue] heterodimers as inhibitors of HIV-1 reverse transcriptase. Nucleosides Nucleotides Nucleic Acids. 2002;21(8-9):505-33. PubMed PMID: 12484448. 2. Sugeac E, Fossey C, Ladur?e D, Schmidt S, Laumond G, Aubertin AM. Synthesis and anti-HIV activity of some heterodimers [NRTI]-glycyl-succinyl-[trovirdine analogue] of known HIV-1 reverse transcriptase inhibitors. J Enzyme Inhib Med Chem. 2003 Apr;18(2):175-86. PubMed PMID: 12943202. 3. Zhang H, Vrang L, B?ckbro K, Lind P, Sahlberg C, Unge T, Oberg B. Inhibition of human immunodeficiency virus type 1 wild-type and mutant reverse transcriptases by the phenyl ethyl thiazolyl thiourea derivatives trovirdine and MSC-127. Antiviral Res. 1995 Dec;28(4):331-42. PubMed PMID: 8669892. 4. Uckun FM, Mao C, Pendergrass S, Maher D, Zhu D, Tuel-Ahlgren L, Venkatachalam TK. N-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-bromopyridyl)]-thiourea and N'-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-chloropyridyl)]-thiourea as potent inhibitors of multidrug-resistant human immunodeficiency virus-1. Bioorg Med Chem Lett. 1999 Sep 20;9(18):2721-6. PubMed PMID: 10509923.