TargetMol

Eprociclovir

Product Code:
 
TAR-T31659
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T31659-1mg1mg£199.00
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TAR-T31659-5mg5mg£392.00
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TAR-T31659-10mg10mg£552.00
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TAR-T31659-25mg25mg£841.00
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TAR-T31659-50mg50mg£1,099.00
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This product comes from: United States.
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Further Information

Bioactivity:
Eprociclovir, also known as A-5021, is a new acyclovir analog and a potent inhibitor of EHV1 replication and may have the potential for the treatment and/or prophylaxis of infections with this virus. Eprociclovir possesses potent anti-herpetic activity against most human herpesviruses.
CAS:
145512-85-2
Formula:
C11H15N5O3
Molecular Weight:
265.273
Pathway:
Microbiology/Virology
Purity:
0.98
SMILES:
Nc1nc2n(C[C@]3(CO)C[C@H]3CO)cnc2c(=O)[nH]1
Target:
Antifection

References

1. Glorieux S, Vandekerckhove AP, Goris N, Yang XY, Steukers L, Van de Walle GR, Croubels S, Neyts J, Nauwynck HJ. Evaluation of the antiviral activity of (1'S,2'R)-9-[[1',2'-bis(hydroxymethyl)cycloprop-1'-yl]methyl]guanine (A-5021) against equine herpesvirus type 1 in cell monolayers and equine nasal mucosal explants. Antiviral Res. 2012 Feb;93(2):234-8. doi: 10.1016/j.antiviral.2011.11.016. Epub 2011 Dec 8. PubMed PMID: 22178244. 2. Ostrowski T, Golankiewicz B, De Clercq E, Andrei G, Snoeck R. Synthesis and anti-VZV activity of 6-heteroaryl derivatives of tricyclic acyclovir and 9-{[cis-1',2'-bis(hydroxymethyl)cycloprop-1'-yl]methyl}guanine analogues. Eur J Med Chem. 2009 Aug;44(8):3313-7. doi: 10.1016/j.ejmech.2009.03.005. Epub 2009 Mar 21. PubMed PMID: 19339082. 3. Itahashi M, Higaki S, Sugahara D, Sugioka K, Deai T, Takao K, Hayashi K, Shimomura Y. A-5021: a new acyclovir analogue inhibits murine herpetic keratitis. Cornea. 2008 Apr;27(3):334-8. doi: 10.1097/ICO.0b013e31815d889b. PubMed PMID: 18362663. 4. De Clercq E, Naesens L. In search of effective anti-HHV-6 agents. J Clin Virol. 2006 Dec;37 Suppl 1:S82-6. Review. PubMed PMID: 17276375.