TargetMol

E 4441

Product Code:
 
TAR-T31590
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T31590-5mg5mg£850.00
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TAR-T31590-50mg50mg£1,661.00
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Quantity:
TAR-T31590-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
E 4441 is a third-generation difluoroquinolone, which has good activity against G(+) aerobic bacteria and anaerobic bacteria in vitro and in vivo.
CAS:
124668-12-8
Formula:
C17H17F2N3O3
Molecular Weight:
349.338
Purity:
0.98
SMILES:
CC1(N)CN(C1)c1c(F)cc2c(c1F)n(cc(C(O)=O)c2=O)C1CC1

References

1. Martinez L, Basi N, Dordal A, Roser R, Sagarra R. A pharmacokinetic study of E-4441, a new quinolone, in the rat, mouse and cynomolgus monkey. Eur J Drug Metab Pharmacokinet. 1991;Spec No 3:352-6. PubMed PMID: 1668199. 2. Esteve M, Moros M, Coll R, Xicota MA, Llovera S. Antimicrobial activity of E-4441, a representative azetidine quinolone. Drugs Exp Clin Res. 1990;16(9):445-9. PubMed PMID: 2100245. 3. Gargallo-Viola D, Esteve M, Moros M, Coll R, Xicota MA, de Andres C, Roser R, Guinea J. Comparative in vitro and in vivo activities of six new monofluoroquinolone and difluoroquinolone 3-carboxylic acids with a 7-azetidin ring substituent. Antimicrob Agents Chemother. 1990 Dec;34(12):2318-26. PubMed PMID: 2088187; PubMed Central PMCID: PMC172054.