TargetMol

Difenamizole

Product Code:
 
TAR-T31454
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T31454-5mg5mg£850.00
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Further Information

Bioactivity:
Difenamizole is a nonsteroidal anti-inflammatory drug (NSAID), which is a pyrazolinone analgesic drug-related to Analgin. It has monoaminergic properties, including inhibition of monoamine oxidase, an increase of pargyline-induced striatal dopamine levels, inhibition of K+ -induced striatal dopamine release, and inhibition of dopamine reuptake.
CAS:
20170-20-1
Formula:
C20H22N4O
Molecular Weight:
334.423
Purity:
0.98
SMILES:
CC(N(C)C)C(=O)Nc1cc(nn1-c1ccccc1)-c1ccccc1

References

1. Kameyama T, Nabeshima T, Yoshida N, Yamaguchi K. Neurochemical studies of an analgesic, 1,3-diphenyl-5-(2-dimethylaminopropionamide)-pyrazole [difenamizole]. Res Commun Chem Pathol Pharmacol. 1981 Jan;31(1):31-53. PubMed PMID: 6454942. 2. Kameyama T, Ukai M, Nabeshima T. Inhibitory effect of difenamizole on morphine-induced straub tail reaction with special reference to monoaminergic agents. Chem Pharm Bull (Tokyo). 1978 Nov;26(11):3265-70. PubMed PMID: 729114. 3. Nabeshima T, Yamaguchi K, Kameyama T. Effects of difenamizole on content of catecholamines and metabolites in mouse brain. Jpn J Pharmacol. 1978 Aug;28(4):642-6. PubMed PMID: 732046. 4. Kameyama T, Nabeshima T. Effects of 1,3-diphenyl-5-(2-dimethylaminopropionamide)-pyrazole[difenamizole] on a conditioned avoidance response. Neuropharmacology. 1978 Apr-May;17(4-5):249-56. PubMed PMID: 652137.