TargetMol

CI 992

Product Code:
 
TAR-T30921
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T30921-5mg5mg£1,733.00
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TAR-T30921-50mg50mg£3,428.00
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Quantity:
TAR-T30921-100mg100mg£4,729.00
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Further Information

Bioactivity:
CI 992 is a novel potent inhibitor of primate renin.
CAS:
135704-06-2
Formula:
C33H52N6O7S2
Molecular Weight:
708.93
Purity:
0.98
SMILES:
CC(C)C[C@H](O)[C@H](O)[C@H](CC1CCCCC1)N[C@@H](Cc1csc(N)n1)C(=O)NC(=O)[C@H](Cc1ccccc1)NS(=O)(=O)N1CCOCC1

References

1. Cook JA, Burger PJ, Michniewicz BM, Nordblom GD, Hicks GW, Kaplan C, Ryan MJ. Pharmacokinetics and pharmacodynamics of CI-992 following intravenous and oral administration to cynomolgus monkeys. Biopharm Drug Dispos. 1998 Apr;19(3):185-91. PubMed PMID: 9570002. 2. Ryan MJ, Hicks GW, Batley BL, Rapundalo ST, Patt WC, Taylor DG, Keiser JA. Effect of an orally active renin inhibitor Cl-992 on blood pressure in normotensive and hypertensive monkeys. J Pharmacol Exp Ther. 1994 Jan;268(1):372-9. PubMed PMID: 8301578.