TargetMol

BMS-284640

Product Code:
 
TAR-T30512
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T30512-5mg5mg£850.00
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Quantity:
TAR-T30512-50mg50mg£1,661.00
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Quantity:
TAR-T30512-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
BMS-284640 is a Na(+)/H(+) exchange agent (NHE) inhibitor that has provided substantial protection in various animal models of myocardial ischemia (MI) and reperfusion in preclinical studies.
CAS:
230640-88-7
Formula:
C15H19N3O2
Molecular Weight:
273.336
Purity:
0.98
SMILES:
CC1(C)[C@@H]([C@H]1c1cccc2OCCc12)C(=O)NC(N)=N

References

1. Masereel B, Pochet L, Laeckmann D. An overview of inhibitors of Na(+)/H(+) exchanger. Eur J Med Chem. 2003 Jun;38(6):547-54. Review. PubMed PMID: 12832126. 2. Ahmad S, Doweyko LM, Dugar S, Grazier N, Ngu K, Wu SC, Yost KJ, Chen BC, Gougoutas JZ, DiMarco JD, Lan SJ, Gavin BJ, Chen AY, Dorso CR, Serafino R, Kirby M, Atwal KS. Arylcyclopropanecarboxyl guanidines as novel, potent, and selective inhibitors of the sodium hydrogen exchanger isoform-1. J Med Chem. 2001 Sep 27;44(20):3302-10. PubMed PMID: 11563929.