TargetMol

ML-7 hydrochloride

Product Code:
 
TAR-T3050
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3050-5mg5mg£104.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3050-1mL1 mL * 10 mM (in DMSO)£107.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3050-10mg10mg£125.00
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Quantity:
TAR-T3050-25mg25mg£193.00
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Quantity:
TAR-T3050-50mg50mg£300.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3050-100mg100mg£368.00
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Quantity:
TAR-T3050-200mg200mg£458.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
ML-7 Hcl is a cell-permeable, reversible, effective, ATP-competitive, and specific inhibitor of myosin light chain kinase (Ki: 300 nM); also inhibits smooth-muscle myosin light chain kinase, PKA, and PKC.
CAS:
110448-33-4
Formula:
C15H18ClIN2O2S
Molecular Weight:
452.74
Pathway:
Cytoskeletal Signaling; Stem Cells; Metabolism; Tyrosine Kinase/Adaptors; Chromatin/Epigenetic; Cell Cycle/Checkpoint
Purity:
0.9961
SMILES:
C1CNCCN(C1)S(=O)(=O)c1cccc2c1cccc2I.Cl
Target:
Serine/threonin kinase; Myosin; YAP; PKA; PKC

References

1. Cheng X, et al. Mol Med Rep. 2015, 12(3):4109-16. 2. Connell LE, et al. J Cell Sci. 2006, 119(Pt 11):2269-81. 3. Saitoh M, et al. J Biol Chem. 1987, 262(16):7796-801. 4. Fazal F, et al. Mol Cell Biol. 2005, 25(14):6259-66. 5. Zhang H, Lin F, Huang J, et al. Anisotropic stiffness gradient-regulated mechanical guidance drives directional migration of cancer cells[J]. Acta Biomaterialia. 2020.