TargetMol

BMS-188494

Product Code:
 
TAR-T30499
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T30499-5mg5mg£850.00
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TAR-T30499-50mg50mg£1,661.00
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Quantity:
TAR-T30499-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
BMS-188494 is a squalene synthase inhibitor used as an anti-cholesterol drug.
CAS:
191866-32-7
Formula:
C28H39O11PS
Molecular Weight:
614.64
Purity:
0.98
SMILES:
CC(C)(C)C(=O)OCOP(=O)(OCOC(=O)C(C)(C)C)[C@@H](CCCc1cccc(Oc2ccccc2)c1)S(O)(=O)=O

References

1. Sharma A, Slugg PH, Hammett JL, Jusko WJ. Clinical pharmacokinetics and pharmacodynamics of a new squalene synthase inhibitor, BMS-188494, in healthy volunteers. J Clin Pharmacol. 1998 Dec;38(12):1116-21. PubMed PMID: 11301563. 2. Flint OP, Masters BA, Gregg RE, Durham SK. Inhibition of cholesterol synthesis by squalene synthase inhibitors does not induce myotoxicity in vitro. Toxicol Appl Pharmacol. 1997 Jul;145(1):91-8. PubMed PMID: 9221828.