TargetMol

AZD 0328

Product Code:
 
TAR-T30247
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T30247-5mg5mg£850.00
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Quantity:
TAR-T30247-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T30247-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
AZD 0328 is a nicotinic receptor agonist for α7 neurons.
CAS:
220099-91-2
Formula:
C13H16N2O
Molecular Weight:
216.284
Purity:
0.98
SMILES:
C1c2cccnc2OC11CN2CCC1CC2

References

1. Zhou D, Zhang M, Ye X, Gu C, Piser TM, Lanoue BA, Schock SA, Cheng YF, Grimm SW. In vitro metabolism of ?7 neuronal nicotinic receptor agonist AZD0328 and enzyme identification for its N-oxide metabolite. Xenobiotica. 2011 Mar;41(3):232-42. doi: 10.3109/00498254.2010.536855. Epub 2011 Jan 13. PubMed PMID: 21226652. 2. Castner SA, Smagin GN, Piser TM, Wang Y, Smith JS, Christian EP, Mrzljak L, Williams GV. Immediate and sustained improvements in working memory after selective stimulation of ?7 nicotinic acetylcholine receptors. Biol Psychiatry. 2011 Jan 1;69(1):12-8. doi: 10.1016/j.biopsych.2010.08.006. Epub 2010 Oct 20. PubMed PMID: 20965497. 3. Sydserff S, Sutton EJ, Song D, Quirk MC, Maciag C, Li C, Jonak G, Gurley D, Gordon JC, Christian EP, Doherty JJ, Hudzik T, Johnson E, Mrzljak L, Piser T, Smagin GN, Wang Y, Widzowski D, Smith JS. Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes. Biochem Pharmacol. 2009 Oct 1;78(7):880-8. doi: 10.1016/j.bcp.2009.07.005. Epub 2009 Jul 16. PubMed PMID: 19615981.