TargetMol

Aplindore Fumarate

Product Code:
 
TAR-T30098
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T30098-1mg1mg£306.00
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TAR-T30098-5mg5mg£659.00
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TAR-T30098-10mg10mg£863.00
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TAR-T30098-25mg25mg£1,299.00
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TAR-T30098-50mg50mg£1,661.00
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Quantity:
TAR-T30098-100mg100mg£2,319.00
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This product comes from: United States.
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Further Information

Bioactivity:
Aplindore Fumarate is a dopamine receptor agonist used to treat Parkinson's disease.
CAS:
189681-71-8
Formula:
C22H22N2O7
Molecular Weight:
426.425
Purity:
0.98
SMILES:
OC(=O)C=CC(O)=O.O=C1Cc2c(N1)ccc1OCC(CNCc3ccccc3)Oc21

References

1. Jackson MJ, Andree TH, Hansard M, Hoffman DC, Hurtt MR, Kehne JH, Pitler TA, Smith LA, Stack G, Jenner P. The dopamine D(2) receptor partial agonist aplindore improves motor deficits in MPTP-treated common marmosets alone and combined with L-dopa. J Neural Transm (Vienna). 2010 Jan;117(1):55-67. doi: 10.1007/s00702-009-0323-9. Epub 2009 Oct 7. PubMed PMID: 19809864. 2. Heinrich JN, Brennan J, Lai MH, Sullivan K, Hornby G, Popiolek M, Jiang LX, Pausch MH, Stack G, Marquis KL, Andree TH. Aplindore (DAB-452), a high affinity selective dopamine D2 receptor partial agonist. Eur J Pharmacol. 2006 Dec 15;552(1-3):36-45. Epub 2006 Sep 14. PubMed PMID: 17056032.