TargetMol

AGN 191976

Product Code:
 
TAR-T29722
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T29722-5mg5mg£850.00
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Further Information

Bioactivity:
AGN 191976 is a novel thromboxane A2-mimetic.
CAS:
159359-94-1
Formula:
C21H34O6
Molecular Weight:
382.497
Purity:
0.98
SMILES:
[H][C@]12C[C@]([H])(OC(=O)O1)[C@H](CC=C/CCCC(O)=O)[C@H]2CC[C@@H](O)CCCCC

References

1. Krauss AH, Woodward DF, Burk RM, Gac TS, Gibson LL, Protzman CE, Abbass F, Marshall K, Senior J. Pharmacological evidence for thromboxane receptor heterogeneity--implications for the eye. J Ocul Pharmacol Ther. 1997 Aug;13(4):303-12. PubMed PMID: 9261766. 2. Abbas F, Amin Z, Burk RM, Krauss AH, Marshall K, Senior J, Woodward DF. A comparative study of thromboxane (TP) receptor mimetics and antagonists on isolated human umbilical artery and myometrium. Adv Exp Med Biol. 1997;407:219-30. PubMed PMID: 9321956. 3. Krauss AH, Woodward DF, Gibson LL, Protzman CE, Williams LS, Burk RM, Gac TS, Roof MB, Abbas F, Marshall K, Senior J. Evidence for human thromboxane receptor heterogeneity using a novel series of 9,11-cyclic carbonate derivatives of prostaglandin F2 alpha. Br J Pharmacol. 1996 Mar;117(6):1171-80. PubMed PMID: 8882612; PubMed Central PMCID: PMC1909759. 4. Krauss AH, Woodward DF, Chen J, Gibson LL, Lai RK, Protzman CE, Shan T, Williams LS, Gac TS, Burk RM. AGN 191976: a novel thromboxane A2-mimetic with ocular hypotensive properties. J Ocul Pharmacol Ther. 1995 Fall;11(3):203-12. PubMed PMID: 8590251.