TargetMol

AG28262 free base

Product Code:
 
TAR-T29706
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T29706-5mg5mg£1,010.00
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Quantity:
TAR-T29706-50mg50mg£1,982.00
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Quantity:
TAR-T29706-100mg100mg£2,560.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
AG28262 is a VEFG-2 inhibitor that increases serum ALT, due in part to both gene up-regulation.
CAS:
638216-89-4
Formula:
C22H18N4O2S2
Molecular Weight:
434.53
Purity:
0.98
SMILES:
CNC(=O)c1c(C)sc2cc(Oc3ccnc4cc(sc34)-c3nccn3C)ccc12

References

1. Fuentealba C, Bera M, Jessen B, Sace F, Stevens GJ, Trajkovic D, Yang AH, Evering W. Evaluation of the effects of a VEGFR-2 inhibitor compound on alanine aminotransferase gene expression and enzymatic activity in the rat liver. Comp Hepatol. 2011 Aug 17;10:8. doi: 10.1186/1476-5926-10-8. PubMed PMID: 21846403; PubMed Central PMCID: PMC3173283. 2. Soda Y, Marumoto T, Friedmann-Morvinski D, Soda M, Liu F, Michiue H, Pastorino S, Yang M, Hoffman RM, Kesari S, Verma IM. Transdifferentiation of glioblastoma cells into vascular endothelial cells. Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4274-80. doi: 10.1073/pnas.1016030108. Epub 2011 Jan 24. PubMed PMID: 21262804; PubMed Central PMCID: PMC3060261.