TargetMol

Germacrone

Product Code:
 
TAR-T2945
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2945-5mg5mg£103.00
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Quantity:
TAR-T2945-1mL1 mL * 10 mM (in DMSO)£113.00
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TAR-T2945-10mg10mg£130.00
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TAR-T2945-25mg25mg£172.00
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TAR-T2945-50mg50mg£201.00
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Quantity:
TAR-T2945-100mg100mg£239.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Germacrone, a major active component found in Curcuma zedoaria oil product, shows anti-inflammatory, antiandrogenic, and antivirus activities. It also inhibits the proliferation of glioma cells by promoting apoptosis.
CAS:
6902-91-6
Formula:
C15H22O
Molecular Weight:
218.33
Pathway:
Metabolism; Immunology/Inflammation; Microbiology/Virology
Purity:
0.9987
SMILES:
C(C)(C)=C1C(=O)CC(C)=C/CC/C(/C)=CC1
Target:
P45; Antiviral; Influenza Virus

References

1. Xie XH, et al. Germacrone reverses Adriamycin resistance through cell apoptosis in multidrug-resistant breast cancer cells. Exp Ther Med. 2014 Nov;8(5):1611-1615. 2. Pimkaew P, et al. Interactions of sesquiterpenes zederone and germacrone with the human cytochrome P450 system. Toxicol In Vitro. 2013 Sep;27(6):2005-12. 3. An JF, et al. The effects of germacrone on lipopolysaccharide-induced acute lung injury in neonatal rats. Cell Mol Biol (Noisy-le-grand). 2014 Nov 16;60(4):8-12.