TargetMol

Uprifosbuvir

Product Code:
 
TAR-T29069
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T29069-5mg5mg£1,251.00
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Quantity:
TAR-T29069-50mg50mg£2,464.00
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Quantity:
TAR-T29069-100mg100mg£3,283.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
Uprifosbuvir is an inhibitor of uridine nucleotide analog HCV NS5B polymerase.
CAS:
1496551-77-9
Formula:
C22H29ClN3O9P
Molecular Weight:
545.91
Purity:
0.98
SMILES:
C[C@@H](C(OC(C)C)=O)N[P@@](OC1=CC=CC=C1)(OC[C@H]2O[C@@H](N(C(N3)=O)C=CC3=O)[C@](C)(Cl)[C@@H]2O)=O

References

1. Regan CP, Morissette P, Regan HK, Travis JJ, Gerenser P, Wen J, Fitzgerald K, Gruver S, DeGeorge JJ, Sannajust FJ. Assessment of the clinical cardiac drug-drug interaction associated with the combination of hepatitis C virus nucleotide inhibitors and amiodarone in guinea pigs and rhesus monkeys. Hepatology. 2016 Jul 30. doi: 10.1002/hep.28752. [Epub ahead of print] PubMed PMID: 27474787. 2. Ramirez S, Mikkelsen LS, Gottwein JM, Bukh J. Robust HCV Genotype 3a Infectious Cell Culture System Permits Identification of Escape Variants With Resistance to Sofosbuvir. Gastroenterology. 2016 Jul 21. pii: S0016-5085(16)34809-0. doi: 10.1053/j.gastro.2016.07.013. [Epub ahead of print] PubMed PMID: 27453546.