TargetMol

UC-781

Product Code:
 
TAR-T29037
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T29037-1mg1mg£224.00
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TAR-T29037-5mg5mg£456.00
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TAR-T29037-10mg10mg£622.00
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TAR-T29037-25mg25mg£938.00
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TAR-T29037-50mg50mg£1,259.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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  • Further Information
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Further Information

Bioactivity:
UC-781 is a non-nucleoside reverse transcriptase inhibitor.
CAS:
178870-32-1
Formula:
C17H18ClNO2S
Molecular Weight:
335.85
Pathway:
Immunology/Inflammation|Microbiology/Virology|Proteases/Proteasome
Purity:
0.98
SMILES:
CC(C)=CCOc1cc(NC(=S)c2ccoc2C)ccc1Cl
Target:
HIV Protease|Antiviral

References

1. McConville C, Friend D. Development and characterisation of a self-microemulsifying drug delivery systems (SMEDDSs) for the vaginal administration of the antiretroviral UC-781. Eur J Pharm Biopharm. 2013 Apr;83(3):322-9. doi: 10.1016/j.ejpb.2012.10.007. PubMed PMID: 23159711. 2. Rezk NL. Development and validation of LC-ESI-MS method for sensitive, accurate and rapid determination of UC-781 in New Zealand white rabbit plasma. Talanta. 2011 Sep 30;85(4):2074-9. doi: 10.1016/j.talanta.2011.07.037. PubMed PMID: 21872060. 3. Goddeeris C, Willems T, Houthoofd K, Martens JA, Van den Mooter G. Dissolution enhancement of the anti-HIV drug UC 781 by formulation in a ternary solid dispersion with TPGS 1000 and Eudragit E100. Eur J Pharm Biopharm. 2008 Nov;70(3):861-8. doi: 10.1016/j.ejpb.2008.07.006. PubMed PMID: 18691650. 4. Goddeeris C, Willems T, Van den Mooter G. Formulation of fast disintegrating tablets of ternary solid dispersions consisting of TPGS 1000 and HPMC 2910 or PVPVA 64 to improve the dissolution of the anti-HIV drug UC 781. Eur J Pharm Sci. 2008 Aug 7;34(4-5):293-302. doi: 10.1016/j.ejps.2008.05.005. PubMed PMID: 18602800.