TargetMol

TASP0390325

Product Code:
 
TAR-T28926
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28926-50mg50mg£704.00
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TAR-T28926-100mg100mg£1,099.00
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Further Information

Bioactivity:
TASP0390325, a potent and orally active V1B receptor antagonist, has antidepressant and anxiolytic activities in rodents.
CAS:
1642187-96-9
Formula:
C25H30Cl2FN5O4
Molecular Weight:
554.44
Purity:
0.98
SMILES:
Cl.CC(C)NC(=O)Cn1c(nc2ncc(OCCCN3CCOCC3)cc2c1=O)-c1ccc(F)c(Cl)c1

References

1. Koga K, Nagai Y, Hanyu M, Yoshinaga M, Chaki S, Ohtake N, Ozaki S, Zhang MR, Suhara T, Higuchi M. High-contrast PET imaging of vasopressin V(1B) receptors with a novel radioligand, (11)C-TASP699. J Nucl Med. 2017 Apr 27. pii: jnumed.116.188698. doi: 10.2967/jnumed.116.188698. [Epub ahead of print] PubMed PMID: 28450560. 2. Iijima M, Yoshimizu T, Shimazaki T, Tokugawa K, Fukumoto K, Kurosu S, Kuwada T, Sekiguchi Y, Chaki S. Antidepressant and anxiolytic profiles of newly synthesized arginine vasopressin V1B receptor antagonists: TASP0233278 and TASP0390325. Br J Pharmacol. 2014 Jul;171(14):3511-25. doi: 10.1111/bph.12699. PubMed PMID: 24654684; PubMed Central PMCID: PMC4105937.